Primary mesenchymal stromal cells in co-culture with leukaemic HL-60 cells are sensitised to cytarabine-induced genotoxicity, while leukaemic cells are protected

Tumour microenvironments are hallmarked in many cancer types. In haematological malignancies, bone marrow (BM) mesenchymal stromal cells (MSC) protect malignant cells from drug-induced cytotoxicity. However, less is known about malignant impact on supportive stroma. Notably, it is unknown whether th...

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Detalles Bibliográficos
Autores principales: Gynn, Liana E, Anderson, Elizabeth, Robinson, Gareth, Wexler, Sarah A, Upstill-Goddard, Gillian, Cox, Christine, May, Jennifer E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Manuscripts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633936/
https://www.ncbi.nlm.nih.gov/pubmed/34505878
http://dx.doi.org/10.1093/mutage/geab033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633936/
https://www.ncbi.nlm.nih.gov/pubmed/34505878
http://dx.doi.org/10.1093/mutage/geab033

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