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Serum Predose Metabolic Profiling for Prediction of Rosuvastatin Pharmacokinetic Parameters in Healthy Volunteers

Rosuvastatin is a well-known lipid-lowering agent generally used for hypercholesterolemia treatment and coronary artery disease prevention. There is a substantial inter-individual variability in the absorption of statins usually caused by genetic polymorphisms leading to a variation in the correspon...

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Detalles Bibliográficos
Autores principales: Silveira, Anne Michelli Reis, Duarte, Gustavo Henrique Bueno, Fernandes, Anna Maria Alves de Piloto, Garcia, Pedro Henrique Dias, Vieira, Nelson Rogerio, Antonio, Marcia Aparecida, Carvalho, Patricia de Oliveira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633954/
https://www.ncbi.nlm.nih.gov/pubmed/34867363
http://dx.doi.org/10.3389/fphar.2021.752960