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Serum Predose Metabolic Profiling for Prediction of Rosuvastatin Pharmacokinetic Parameters in Healthy Volunteers
Rosuvastatin is a well-known lipid-lowering agent generally used for hypercholesterolemia treatment and coronary artery disease prevention. There is a substantial inter-individual variability in the absorption of statins usually caused by genetic polymorphisms leading to a variation in the correspon...
Autores principales: | Silveira, Anne Michelli Reis, Duarte, Gustavo Henrique Bueno, Fernandes, Anna Maria Alves de Piloto, Garcia, Pedro Henrique Dias, Vieira, Nelson Rogerio, Antonio, Marcia Aparecida, Carvalho, Patricia de Oliveira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633954/ https://www.ncbi.nlm.nih.gov/pubmed/34867363 http://dx.doi.org/10.3389/fphar.2021.752960 |
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