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Next generation Fc scaffold for multispecific antibodies

Bispecific antibodies (Bispecifics) demonstrate exceptional clinical potential to address some of the most complex diseases. However, Bispecific production in a single cell often requires the correct pairing of multiple polypeptide chains for desired assembly. This is a considerable hurdle that hind...

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Detalles Bibliográficos
Autores principales: Estes, Bram, Sudom, Athena, Gong, Danyang, Whittington, Douglas A., Li, Vivian, Mohr, Christopher, Li, Danqing, Riley, Timothy P., Shi, Stone D.-H., Zhang, Jun, Garces, Fernando, Wang, Zhulun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633962/
https://www.ncbi.nlm.nih.gov/pubmed/34877503
http://dx.doi.org/10.1016/j.isci.2021.103447