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Logical and experimental modeling of cytokine and eicosanoid signaling in psoriatic keratinocytes

Psoriasis is a chronic skin disease, in which immune cells and keratinocytes keep each other in a state of inflammation. It is believed that phospholipase A(2) (PLA(2))-dependent eicosanoid release plays a key role in this. T-helper (Th) 1-derived cytokines are established activators of phospholipas...

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Detalles Bibliográficos
Autores principales: Tsirvouli, Eirini, Ashcroft, Felicity, Johansen, Berit, Kuiper, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633970/
https://www.ncbi.nlm.nih.gov/pubmed/34877506
http://dx.doi.org/10.1016/j.isci.2021.103451