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Logical and experimental modeling of cytokine and eicosanoid signaling in psoriatic keratinocytes
Psoriasis is a chronic skin disease, in which immune cells and keratinocytes keep each other in a state of inflammation. It is believed that phospholipase A(2) (PLA(2))-dependent eicosanoid release plays a key role in this. T-helper (Th) 1-derived cytokines are established activators of phospholipas...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633970/ https://www.ncbi.nlm.nih.gov/pubmed/34877506 http://dx.doi.org/10.1016/j.isci.2021.103451 |