Cargando…

DNA repair factor KAT5 prevents ischemic acute kidney injury through glomerular filtration regulation

The “preconditioning effect” in AKI is a phenomenon in which an episode of ischemia-reperfusion results in tolerance to subsequent ischemia-reperfusion injury. However, its relationship between DNA damage repair has not been elucidated. Here, we show the role of KAT5 in the preconditioning effect. P...

Descripción completa

Detalles Bibliográficos
Autores principales: Hishikawa, Akihito, Hayashi, Kaori, Kubo, Akiko, Miyashita, Kazutoshi, Hashiguchi, Akinori, Kinouchi, Kenichiro, Yoshimoto, Norifumi, Nakamichi, Ran, Akashio, Riki, Sugita, Erina, Azegami, Tatsuhiko, Monkawa, Toshiaki, Suematsu, Makoto, Itoh, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633972/
https://www.ncbi.nlm.nih.gov/pubmed/34877495
http://dx.doi.org/10.1016/j.isci.2021.103436