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Retinoic acid signaling drives differentiation toward the absorptive lineage in colorectal cancer

Retinoic acid (RA) signaling is an important and conserved pathway that regulates cellular proliferation and differentiation. Furthermore, perturbed RA signaling is implicated in cancer initiation and progression. However, the mechanisms by which RA signaling contributes to homeostasis, malignant tr...

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Detalles Bibliográficos
Autores principales: Wester, Roelof A., van Voorthuijsen, Lisa, Neikes, Hannah K., Dijkstra, Jelmer J., Lamers, Lieke A., Frölich, Siebren, van der Sande, Maarten, Logie, Colin, Lindeboom, Rik G.H., Vermeulen, Michiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633980/
https://www.ncbi.nlm.nih.gov/pubmed/34877501
http://dx.doi.org/10.1016/j.isci.2021.103444