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Retinoic acid signaling drives differentiation toward the absorptive lineage in colorectal cancer
Retinoic acid (RA) signaling is an important and conserved pathway that regulates cellular proliferation and differentiation. Furthermore, perturbed RA signaling is implicated in cancer initiation and progression. However, the mechanisms by which RA signaling contributes to homeostasis, malignant tr...
Autores principales: | Wester, Roelof A., van Voorthuijsen, Lisa, Neikes, Hannah K., Dijkstra, Jelmer J., Lamers, Lieke A., Frölich, Siebren, van der Sande, Maarten, Logie, Colin, Lindeboom, Rik G.H., Vermeulen, Michiel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633980/ https://www.ncbi.nlm.nih.gov/pubmed/34877501 http://dx.doi.org/10.1016/j.isci.2021.103444 |
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