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Neurogenic-dependent changes in hippocampal circuitry underlie the procognitive effect of exercise in aging mice

We have shown that the improvement in hippocampal-based learning in aged mice following physical exercise observed is dependent on neurogenesis in the dentate gyrus (DG) and is regulated by changes in growth hormone levels. The changes in neurocircuitry, however, which may underlie this improvement,...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaoqing Alice, Blackmore, Daniel G., Zhuo, Junjie, Nasrallah, Fatima A., To, XuanVinh, Kurniawan, Nyoman D., Carlisle, Alison, Vien, King-Year, Chuang, Kai-Hsiang, Jiang, Tianzi, Bartlett, Perry F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8633984/
https://www.ncbi.nlm.nih.gov/pubmed/34877505
http://dx.doi.org/10.1016/j.isci.2021.103450