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Randomised controlled trial comparing rituximab to mycophenolate mofetil in children and young adults with steroid-dependent idiopathic nephrotic syndrome: study protocol

INTRODUCTION: Glucocorticoids induce remission in 90% of children with idiopathic nephrotic syndrome (INS). Some become steroid-dependent (SD) and require the addition of steroid sparing drugs such as calcineurin-inhibitors (CNI) or cyclophosphamide, to maintain remission. Considering the toxicity o...

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Detalles Bibliográficos
Autores principales: Lugani, Francesca, Angeletti, Andrea, Ravani, Pietro, Vivarelli, Marina, Colucci, Manuela, Caridi, Gianluca, Verrina, Enrico, Emma, Francesco, Ghiggeri, Gian Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634023/
https://www.ncbi.nlm.nih.gov/pubmed/34845071
http://dx.doi.org/10.1136/bmjopen-2021-052450