Assessing a 6-h endpoint observation time in the lethality neutralization assay used to evaluate the preclinical efficacy of snake antivenoms

The lethality neutralization assay in mice is the gold standard for the evaluation of the preclinical efficacy and specification fulfillment of snake antivenoms. However, owing to the animal suffering involved, this assay is a candidate to be replaced by in vitro alternatives or, at least, improved...

Descripción completa

Detalles Bibliográficos
Autores principales: Durán, Gina, Solano, Gabriela, Gómez, Aarón, Cordero, Daniel, Sánchez, Adriana, Villalta, Mauren, Sánchez, Melvin, Díaz, Cecilia, Gutiérrez, José María, León, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634039/
https://www.ncbi.nlm.nih.gov/pubmed/34888521
http://dx.doi.org/10.1016/j.toxcx.2021.100087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634039/
https://www.ncbi.nlm.nih.gov/pubmed/34888521
http://dx.doi.org/10.1016/j.toxcx.2021.100087

Ejemplares similares