Interrogating cell type-specific cooperation of transcriptional regulators in 3D chromatin

Context-specific activities of transcription regulators (TRs) in the nucleus modulate spatiotemporal gene expression precisely. Using the largest ChIP-seq data and chromatin loops in the human K562 cell line, we initially interrogated TR cooperation in 3D chromatin via a graphical model and revealed...

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Detalles Bibliográficos
Autores principales: Yi, Xianfu, Zheng, Zhanye, Xu, Hang, Zhou, Yao, Huang, Dandan, Wang, Jianhua, Feng, Xiangling, Zhao, Ke, Fan, Xutong, Zhang, Shijie, Dong, Xiaobao, Wang, Zhao, Shen, Yujun, Cheng, Hui, Shi, Lei, Li, Mulin Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634045/
https://www.ncbi.nlm.nih.gov/pubmed/34888502
http://dx.doi.org/10.1016/j.isci.2021.103468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634045/
https://www.ncbi.nlm.nih.gov/pubmed/34888502
http://dx.doi.org/10.1016/j.isci.2021.103468

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