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Sex modifies APOE ε4 dose effect on brain tau deposition in cognitively impaired individuals

Recent studies in cognitively unimpaired elderly individuals suggest that the APOE ε4 allele exerts a dosage-dependent effect on brain tau deposition. The aim of this study was to investigate sex differences in APOE ε4 gene dosage effects on brain tau deposition in cognitively impaired individuals u...

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Detalles Bibliográficos
Autores principales: Yan, Shaozhen, Zheng, Chaojie, Paranjpe, Manish D, Li, Yanxiao, Li, Weihua, Wang, Xiuying, Benzinger, Tammie L S, Lu, Jie, Zhou, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634082/
https://www.ncbi.nlm.nih.gov/pubmed/33876815
http://dx.doi.org/10.1093/brain/awab160