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N-Acetyl Cysteine Restores Sirtuin-6 and Decreases HMGB1 Release Following Lipopolysaccharide-Sensitized Hypoxic-Ischemic Brain Injury in Neonatal Mice
Inflammation and neonatal hypoxia-ischemia (HI) are important etiological factors of perinatal brain injury. However, underlying mechanisms remain unclear. Sirtuins are a family of nicotinamide adenine dinucleotide (NAD)+-dependent histone deacetylases. Sirtuin-6 is thought to regulate inflammatory...
Autores principales: | Singh-Mallah, Gagandeep, Kawamura, Takuya, Ardalan, Maryam, Chumak, Tetyana, Svedin, Pernilla, Arthur, Peter G., James, Christopher, Hagberg, Henrik, Sandberg, Mats, Mallard, Carina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634142/ https://www.ncbi.nlm.nih.gov/pubmed/34867200 http://dx.doi.org/10.3389/fncel.2021.743093 |
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