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Phase I study of selinexor in combination with dexamethasone, ifosfamide, carboplatin, etoposide chemotherapy in patients with relapsed or refractory peripheral T-cell or natural-killer/T-cell lymphoma

Selinexor is a selective inhibitor of nuclear export with anti-cancer properties. We performed a phase I study to determine the safety and maximum tolerated dose of selinexor when combined with high-dose dexamethasone, ifosfamide, carboplatin and etoposide (DICE) in relapsed/refractory T-cell lympho...

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Detalles Bibliográficos
Autores principales: Tang, Tiffany, Martin, Peter, Somasundaram, Nagavalli, Lim, Cindy, Tao, Miriam, Poon, Eileen, Yunon, Maica J.D., Toh, Shu Q., Yan, Sean X., Farid, Mohamad, Chan, Jason Y., Lim, Soon T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634181/
https://www.ncbi.nlm.nih.gov/pubmed/33147935
http://dx.doi.org/10.3324/haematol.2020.251454