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Expression of the chemokine receptor CCR1 promotes the dissemination of multiple myeloma plasma cells in vivo
Multiple myeloma (MM) disease progression is dependent on the ability of MM plasma cells (PC) to egress from the bone marrow (BM), enter the circulation and disseminate to distal BM sites. Expression of the chemokine CXCL12 by BM stromal cells is crucial for MM PC retention within the BM. However, t...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Fondazione Ferrata Storti
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634189/ https://www.ncbi.nlm.nih.gov/pubmed/33147936 http://dx.doi.org/10.3324/haematol.2020.253526 |