Cargando…

Expression of the chemokine receptor CCR1 promotes the dissemination of multiple myeloma plasma cells in vivo

Multiple myeloma (MM) disease progression is dependent on the ability of MM plasma cells (PC) to egress from the bone marrow (BM), enter the circulation and disseminate to distal BM sites. Expression of the chemokine CXCL12 by BM stromal cells is crucial for MM PC retention within the BM. However, t...

Descripción completa

Detalles Bibliográficos
Autores principales: Zeissig, Mara N., Hewett, Duncan R., Panagopoulos, Vasilios, Mrozik, Krzysztof M., To, L. Bik, Croucher, Peter I., Zannettino, Andrew C.W., Vandyke, Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634189/
https://www.ncbi.nlm.nih.gov/pubmed/33147936
http://dx.doi.org/10.3324/haematol.2020.253526