Cell-specific expression of Hfe determines the outcome of Salmonella enterica serovar Typhimurium infection in mice

Mutations in HFE cause hereditary hemochromatosis type I hallmarked by increased iron absorption, iron accumulation in hepatocytes and iron deficiency in myeloid cells. HFE encodes an MHC-I like molecule, but its function in immune responses to infection remains incompletely understood. Here, we inv...

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Detalles Bibliográficos
Autores principales: Nairz, Manfred, Metzendorf, Christoph, Vujic-Spasic, Maja, Mitterstiller, Anna-Maria, Schroll, Andrea, Haschka, David, Hoffmann, Alexander, von Raffay, Laura, Sparla, Richard, Huck, Christian W., Talasz, Heribert, Moser, Patrizia L., Muckenthaler, Martina U., Weiss, Günter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634192/
https://www.ncbi.nlm.nih.gov/pubmed/33054105
http://dx.doi.org/10.3324/haematol.2019.241745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634192/
https://www.ncbi.nlm.nih.gov/pubmed/33054105
http://dx.doi.org/10.3324/haematol.2019.241745

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