PVRIG is a novel natural killer cell immune checkpoint receptor in acute myeloid leukemia

This study explored the novel immune checkpoint poliovirus receptor- related immunoglobulin domain-containing (PVRIG) in acute myeloid leukemia (AML). We showed that AML patient blasts consistently expressed the PVRIG ligand (poliovirus receptor-related 2, PVRL2). Furthermore, PVRIG blockade signifi...

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Detalles Bibliográficos
Autores principales: Li, Jessica, Whelan, Sarah, Kotturi, Maya F., Meyran, Deborah, D’Souza, Criselle, Hansen, Kyle, Liang, Spencer, Hunter, John, Trapani, Joseph A., Neeson, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634199/
https://www.ncbi.nlm.nih.gov/pubmed/33147937
http://dx.doi.org/10.3324/haematol.2020.258574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634199/
https://www.ncbi.nlm.nih.gov/pubmed/33147937
http://dx.doi.org/10.3324/haematol.2020.258574

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