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Topiramate-induced severe electrolyte abnormalities and hypernatremia leading to central pontine myelinolysis

Central pontine myelinolysis (CPM) develops due to acute hypernatremia from a normal baseline serum sodium in the setting of electrolyte abnormalities induced by topiramate use. Topiramate is a commonly used medication with several indications including migraines, myoclonic jerks and seizures. It ha...

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Detalles Bibliográficos
Autores principales: Muaddi, Luba, Osman, Omar, Clark, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634286/
https://www.ncbi.nlm.nih.gov/pubmed/34848414
http://dx.doi.org/10.1136/bcr-2021-245870