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Therapeutic Development by Targeting the cGAS-STING Pathway in Autoimmune Disease and Cancer

DNA immune recognition regulation mediated by the cGAS-STING pathway plays an important role in immune functions. Under normal physiological conditions, cGAS can recognize and bind to invading pathogen DNA and activate the innate immune response. On the other hand, abnormal activation of cGAS or STI...

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Detalles Bibliográficos
Autores principales: Li, Qiumei, Tian, Shuoran, Liang, Jiadi, Fan, Jiqiang, Lai, Junzhong, Chen, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634458/
https://www.ncbi.nlm.nih.gov/pubmed/34867409
http://dx.doi.org/10.3389/fphar.2021.779425