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Kinetic modeling reveals additional regulation at co-transcriptional level by post-transcriptional sRNA regulators

Small RNAs (sRNAs) are important gene regulators in bacteria. Many sRNAs act post-transcriptionally by affecting translation and degradation of the target mRNAs upon base-pairing interactions. Here we present a general approach combining imaging and mathematical modeling to determine kinetic paramet...

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Detalles Bibliográficos
Autores principales: Reyer, Matthew A., Chennakesavalu, Shriram, Heideman, Emily M., Ma, Xiangqian, Bujnowska, Magda, Hong, Lu, Dinner, Aaron R., Vanderpool, Carin K., Fei, Jingyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634553/
https://www.ncbi.nlm.nih.gov/pubmed/34592145
http://dx.doi.org/10.1016/j.celrep.2021.109764