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Kinetic modeling reveals additional regulation at co-transcriptional level by post-transcriptional sRNA regulators
Small RNAs (sRNAs) are important gene regulators in bacteria. Many sRNAs act post-transcriptionally by affecting translation and degradation of the target mRNAs upon base-pairing interactions. Here we present a general approach combining imaging and mathematical modeling to determine kinetic paramet...
Autores principales: | Reyer, Matthew A., Chennakesavalu, Shriram, Heideman, Emily M., Ma, Xiangqian, Bujnowska, Magda, Hong, Lu, Dinner, Aaron R., Vanderpool, Carin K., Fei, Jingyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634553/ https://www.ncbi.nlm.nih.gov/pubmed/34592145 http://dx.doi.org/10.1016/j.celrep.2021.109764 |
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