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Processing of RNA Containing 8-Oxo-7,8-Dihydroguanosine (8-oxoG) by the Exoribonuclease Xrn-1

Understanding how oxidatively damaged RNA is handled intracellularly is of relevance due to the link between oxidized RNA and the progression/development of some diseases as well as aging. Among the ribonucleases responsible for the decay of modified (chemically or naturally) RNA is the exonuclease...

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Detalles Bibliográficos
Autores principales: Phillips, Cheyenne N., Schowe, Shawn, Langeberg, Conner J., Siddique, Namoos, Chapman, Erich G., Resendiz, Marino J. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634602/
https://www.ncbi.nlm.nih.gov/pubmed/34869601
http://dx.doi.org/10.3389/fmolb.2021.780315