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CFTR limits F‐actin formation and promotes morphological alignment with flow in human lung microvascular endothelial cells

Micro‐ and macrovascular endothelial dysfunction in response to shear stress has been observed in cystic fibrosis (CF), and has been associated with inflammation and oxidative stress. We tested the hypothesis that the cystic fibrosis transmembrane conductance regulator (CFTR) regulates endothelial a...

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Detalles Bibliográficos
Autores principales: Causer, Adam J., Khalaf, Maha, Klein Rot, Emily, Brand, Kimberly, Smith, James, Bailey, Stephen J., Cummings, Michael H., Shepherd, Anthony I., Saynor, Zoe L., Shute, Janis K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634629/
https://www.ncbi.nlm.nih.gov/pubmed/34851051
http://dx.doi.org/10.14814/phy2.15128