An Unbound Proline-Rich Signaling Peptide Frequently Samples Cis Conformations in Gaussian Accelerated Molecular Dynamics Simulations

Disordered proline-rich motifs are common across the proteomes of many species and are often involved in protein-protein interactions. Proline is a unique amino acid due to the covalent bond between the backbone nitrogen and the proline side chain. The resulting five-membered ring allows proline to...

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Detalles Bibliográficos
Autores principales: Alcantara, Juan, Stix, Robyn, Huang, Katherine, Connor, Acadia, East, Ray, Jaramillo-Martinez, Valeria, Stollar, Elliott J., Ball, K. Aurelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634643/
https://www.ncbi.nlm.nih.gov/pubmed/34869581
http://dx.doi.org/10.3389/fmolb.2021.734169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634643/
https://www.ncbi.nlm.nih.gov/pubmed/34869581
http://dx.doi.org/10.3389/fmolb.2021.734169

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