Epithelial Aryl Hydrocarbon Receptor Protects From Mucus Production by Inhibiting ROS-Triggered NLRP3 Inflammasome in Asthma

BACKGROUND: Despite long-standing recognition in the significance of mucus overproduction in asthma, its etiology remains poorly understood. Muc5ac is a secretory mucin that has been associated with reduced pulmonary function and asthma exacerbations. OBJECTIVES: We sought to investigate the immunol...

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Detalles Bibliográficos
Autores principales: Hu, Xinyue, Shen, Yingchun, Zhao, Yilin, Wang, Ji, Zhang, Xin, Tu, Wei, Kaufman, William, Feng, Juntao, Gao, Peisong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634667/
https://www.ncbi.nlm.nih.gov/pubmed/34868022
http://dx.doi.org/10.3389/fimmu.2021.767508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634667/
https://www.ncbi.nlm.nih.gov/pubmed/34868022
http://dx.doi.org/10.3389/fimmu.2021.767508

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