The Gut Microbiota Metabolite Urolithin B Improves Cognitive Deficits by Inhibiting Cyt C-Mediated Apoptosis and Promoting the Survival of Neurons Through the PI3K Pathway in Aging Mice

Background: Despite considerable advances in pharmacotherapy, more effective therapeutic interventions for aging-related neurodegenerative disorders (NDs), such as Alzheimer’s disease (AD), remain limited. Urolithin B (UB), one of the major subcategories of urolithins (microbiota metabolites) found...

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Detalles Bibliográficos
Autores principales: Chen, Peng, Chen, Fuchao, Lei, Jiexin, Wang, Gaohua, Zhou, Benhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634731/
https://www.ncbi.nlm.nih.gov/pubmed/34867396
http://dx.doi.org/10.3389/fphar.2021.768097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8634731/
https://www.ncbi.nlm.nih.gov/pubmed/34867396
http://dx.doi.org/10.3389/fphar.2021.768097

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