Up-Regulation of p53/miR-628-3p Pathway, a Novel Mechanism of Shikonin on Inhibiting Proliferation and Inducing Apoptosis of A549 and PC-9 Non–Small Cell Lung Cancer Cell Lines

Shikonin (SHK) is a pleiotropic agent with remarkable cell growth inhibition activity against various cancer types, especially non–small cell lung cancer (NSCLC), but its molecular mechanism is still unclear. Our previous study found that miR-628-3p could inhibit the growth of A549 cells and induce...

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Detalles Bibliográficos
Autores principales: Pan, Jieli, Li, Meiya, Yu, Fenglin, Zhu, Feiye, Wang, Linyan, Ning, Dandan, Hou, Xiaoli, Jiang, Fusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635033/
https://www.ncbi.nlm.nih.gov/pubmed/34867391
http://dx.doi.org/10.3389/fphar.2021.766165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635033/
https://www.ncbi.nlm.nih.gov/pubmed/34867391
http://dx.doi.org/10.3389/fphar.2021.766165

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