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Evaluation of Safety and Protective Efficacy of a waaJ and spiC Double Deletion Korean Epidemic Strain of Salmonella enterica Serovar Gallinarum

With an aim to develop a highly attenuated and strongly immunogenic distinguishable vaccine candidate, a waaJ (a gene involved in the synthesis of lipopolysaccharide) and spiC (a virulence gene) double deletion Korean epidemic strain of S. enterica ser. Gallinarum (SG005) was constructed. Our result...

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Detalles Bibliográficos
Autores principales: Zhang, Jun-Feng, Shang, Ke, Wei, Bai, Lee, Yea-Jin, Park, Jong-Yeol, Jang, Hyung-Kwan, Cha, Se-Yeoun, Kang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635151/
https://www.ncbi.nlm.nih.gov/pubmed/34869728
http://dx.doi.org/10.3389/fvets.2021.756123