HIV-1 induced changes in HLA-C∗03 : 04-presented peptide repertoires lead to reduced engagement of inhibitory natural killer cell receptors

OBJECTIVE: Viral infections influence intracellular peptide repertoires available for presentation by HLA-I. Alterations in HLA-I/peptide complexes can modulate binding of killer immunoglobuline-like receptors (KIRs) and thereby the function of natural killer (NK) cells. Although multiple studies ha...

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Detalles Bibliográficos
Autores principales: Ziegler, Maja C., Nelde, Annika, Weber, Jeffrey K., Schreitmüller, Christian M., Martrus, Glòria, Huynh, Tien, Bunders, Madeleine J., Lunemann, Sebastian, Stevanovic, Stefan, Zhou, Ruhong, Altfeld, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635260/
https://www.ncbi.nlm.nih.gov/pubmed/32501836
http://dx.doi.org/10.1097/QAD.0000000000002596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635260/
https://www.ncbi.nlm.nih.gov/pubmed/32501836
http://dx.doi.org/10.1097/QAD.0000000000002596

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