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HIV-1 induced changes in HLA-C∗03 : 04-presented peptide repertoires lead to reduced engagement of inhibitory natural killer cell receptors
OBJECTIVE: Viral infections influence intracellular peptide repertoires available for presentation by HLA-I. Alterations in HLA-I/peptide complexes can modulate binding of killer immunoglobuline-like receptors (KIRs) and thereby the function of natural killer (NK) cells. Although multiple studies ha...
Autores principales: | Ziegler, Maja C., Nelde, Annika, Weber, Jeffrey K., Schreitmüller, Christian M., Martrus, Glòria, Huynh, Tien, Bunders, Madeleine J., Lunemann, Sebastian, Stevanovic, Stefan, Zhou, Ruhong, Altfeld, Marcus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635260/ https://www.ncbi.nlm.nih.gov/pubmed/32501836 http://dx.doi.org/10.1097/QAD.0000000000002596 |
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