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A unified drug–target interaction prediction framework based on knowledge graph and recommendation system

Prediction of drug-target interactions (DTI) plays a vital role in drug development in various areas, such as virtual screening, drug repurposing and identification of potential drug side effects. Despite extensive efforts have been invested in perfecting DTI prediction, existing methods still suffe...

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Detalles Bibliográficos
Autores principales: Ye, Qing, Hsieh, Chang-Yu, Yang, Ziyi, Kang, Yu, Chen, Jiming, Cao, Dongsheng, He, Shibo, Hou, Tingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635420/
https://www.ncbi.nlm.nih.gov/pubmed/34811351
http://dx.doi.org/10.1038/s41467-021-27137-3