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Transcriptional control of mycobacterial DNA damage response by sigma adaptation

Transcriptional activator PafBC is the key regulator of the mycobacterial DNA damage response and controls around 150 genes, including genes involved in the canonical SOS response, through an unknown molecular mechanism. Using a combination of biochemistry and cryo–electron microscopy, we demonstrat...

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Detalles Bibliográficos
Autores principales: Müller, Andreas U., Kummer, Eva, Schilling, Charlotte M., Ban, Nenad, Weber-Ban, Eilika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635444/
https://www.ncbi.nlm.nih.gov/pubmed/34851662
http://dx.doi.org/10.1126/sciadv.abl4064