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Transcriptional control of mycobacterial DNA damage response by sigma adaptation
Transcriptional activator PafBC is the key regulator of the mycobacterial DNA damage response and controls around 150 genes, including genes involved in the canonical SOS response, through an unknown molecular mechanism. Using a combination of biochemistry and cryo–electron microscopy, we demonstrat...
Autores principales: | Müller, Andreas U., Kummer, Eva, Schilling, Charlotte M., Ban, Nenad, Weber-Ban, Eilika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635444/ https://www.ncbi.nlm.nih.gov/pubmed/34851662 http://dx.doi.org/10.1126/sciadv.abl4064 |
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