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Therapeutic implications of ongoing alveolar viral replication in COVID-19

In patients with moderate-to-severe COVID-19 pneumonia, an aberrant post-viral alveolitis with excessive inflammatory responses and immunothrombosis underpins use of immunomodulatory therapy (eg, corticosteroids and interleukin-6 receptor antagonism). By contrast, immunosuppression in individuals wi...

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Detalles Bibliográficos
Autores principales: McGonagle, Dennis, Kearney, Mary F, O'Regan, Anthony, O'Donnell, James S, Quartuccio, Luca, Watad, Abdulla, Bridgewood, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635460/
https://www.ncbi.nlm.nih.gov/pubmed/34873587
http://dx.doi.org/10.1016/S2665-9913(21)00322-2