Reduced preload increases Mechanical Control (strain-rate dependence) of Relaxation by modifying myosin kinetics

Rapid myocardial relaxation is essential in maintaining cardiac output, and impaired relaxation is an early indicator of diastolic dysfunction. While the biochemical modifiers of relaxation are well known to include calcium handling, thin filament activation, and myosin kinetics, biophysical and bio...

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Detalles Bibliográficos
Autores principales: Schick, Brianna M., Dlugas, Hunter, Czeiszperger, Teresa L., Matus, Alexandra R., Bukowski, Melissa J., Chung, Charles S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635462/
https://www.ncbi.nlm.nih.gov/pubmed/34015323
http://dx.doi.org/10.1016/j.abb.2021.108909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635462/
https://www.ncbi.nlm.nih.gov/pubmed/34015323
http://dx.doi.org/10.1016/j.abb.2021.108909

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