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Pharmacokinetic study on the interaction between succinic acid and irbesartan in rats and its potential mechanism

CONTEXT: Succinic acid and irbesartan are commonly used drugs in cardiovascular disease treatment. The interaction might occur during their co-administration, which was still unclear. OBJECTIVE: To reveal the effect of succinic acid on the metabolism of irbesartan and its potential mechanism. MATERI...

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Detalles Bibliográficos
Autores principales: Wang, Yongpeng, Rui, Ruping, Zhang, Xiaoyan, Sun, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635542/
https://www.ncbi.nlm.nih.gov/pubmed/34818122
http://dx.doi.org/10.1080/13880209.2021.2002370