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Protective effect of Qingre Huoxue decoction against myocardial infarction via PI3K/Akt autophagy pathway based on UPLC-MS, network pharmacology, and in vivo evidence

CONTEXT: Qingre Huoxue (QRHX) decoction, a traditional Chinese medicine, has been widely used to prevent and treat myocardial infarction (MI). OBJECTIVE: This study elucidates the possible mechanisms of QRHX in preventing or treating MI in a rat model. MATERIALS AND METHODS: The chemical constituent...

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Detalles Bibliográficos
Autores principales: Jin, Zheng, Zhang, Wenbo, Luo, Yuan, Li, Xiushen, Qing, Lijin, Zuo, Qiang, Fang, Junfeng, Wu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635559/
https://www.ncbi.nlm.nih.gov/pubmed/34818128
http://dx.doi.org/10.1080/13880209.2021.2001542