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Protective effect of Qingre Huoxue decoction against myocardial infarction via PI3K/Akt autophagy pathway based on UPLC-MS, network pharmacology, and in vivo evidence
CONTEXT: Qingre Huoxue (QRHX) decoction, a traditional Chinese medicine, has been widely used to prevent and treat myocardial infarction (MI). OBJECTIVE: This study elucidates the possible mechanisms of QRHX in preventing or treating MI in a rat model. MATERIALS AND METHODS: The chemical constituent...
Autores principales: | Jin, Zheng, Zhang, Wenbo, Luo, Yuan, Li, Xiushen, Qing, Lijin, Zuo, Qiang, Fang, Junfeng, Wu, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635559/ https://www.ncbi.nlm.nih.gov/pubmed/34818128 http://dx.doi.org/10.1080/13880209.2021.2001542 |
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