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Whole-Exome Sequencing Reveals Recurrent but Heterogeneous Mutational Profiles in Sporadic WHO Grade 1 Meningiomas

Human WHO grade 1 meningiomas are generally considered benign tumors; despite this, they account for ≈50% of all recurrent meningiomas. Currently, limited data exist about the mutational profiles of grade 1 meningiomas and patient outcome. We investigated the genetic variants present in 32 WHO grade...

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Detalles Bibliográficos
Autores principales: González-Tablas, María, Prieto, Carlos, Arandia, Daniel, Jara-Acevedo, María, Otero, Álvaro, Pascual, Daniel, Ruíz, Laura, Álvarez-Twose, Iván, García-Montero, Andrés Celestino, Orfao, Alberto, Tabernero, María Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635692/
https://www.ncbi.nlm.nih.gov/pubmed/34868937
http://dx.doi.org/10.3389/fonc.2021.740782