Cargando…

Loss of mDia1 and Fhod1 impacts platelet formation but not platelet function

An organized and dynamic cytoskeleton is required for platelet formation and function. Formins are a large family of actin regulatory proteins which are also able to regulate microtubule dynamics. There are four formin family members expressed in human and mouse megakaryocytes and platelets. We have...

Descripción completa

Detalles Bibliográficos
Autores principales: Zuidscherwoude, Malou, Haining, Elizabeth J., Simms, Victoria A., Watson, Stephanie, Grygielska, Beata, Hardy, Alex T., Bacon, Andrea, Watson, Stephen P., Thomas, Steven G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635707/
https://www.ncbi.nlm.nih.gov/pubmed/32981398
http://dx.doi.org/10.1080/09537104.2020.1822522