Mutation in Irf8 Gene (Irf8(R294C) ) Impairs Type I IFN-Mediated Antiviral Immune Response by Murine pDCs

Plasmacytoid dendritic cells (pDCs) are the key producers of type I interferons (IFNs), thus playing a central role in initiating antiviral immune response. Besides robust type I IFN production, pDCs also act as antigen presenting cells post immunogenic stimulation. Transcription factor Irf8 is indi...

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Detalles Bibliográficos
Autores principales: Das, Annesa, Chauhan, Kuldeep Singh, Kumar, Himanshu, Tailor, Prafullakumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635750/
https://www.ncbi.nlm.nih.gov/pubmed/34867997
http://dx.doi.org/10.3389/fimmu.2021.758190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635750/
https://www.ncbi.nlm.nih.gov/pubmed/34867997
http://dx.doi.org/10.3389/fimmu.2021.758190

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