Post-weaning Social Isolated Flinders Sensitive Line Rats Display Bio-Behavioural Manifestations Resistant to Fluoxetine: A Model of Treatment-Resistant Depression

Treatment-resistant depression (TRD) complicates the management of major depression (MD). The underlying biology of TRD involves interplay between genetic propensity and chronic and/or early life adversity. By combining a genetic animal model of MD and post-weaning social isolation rearing (SIR), we...

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Detalles Bibliográficos
Autores principales: Mncube, Khulekani, Möller, Marisa, Harvey, Brian H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635751/
https://www.ncbi.nlm.nih.gov/pubmed/34867504
http://dx.doi.org/10.3389/fpsyt.2021.688150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635751/
https://www.ncbi.nlm.nih.gov/pubmed/34867504
http://dx.doi.org/10.3389/fpsyt.2021.688150

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