Disentangling bias between G(q), GRK2, and arrestin3 recruitment to the M(3) muscarinic acetylcholine receptor

G protein-coupled receptors (GPCRs) transmit extracellular signals to the inside by activation of intracellular effector proteins. Different agonists can promote differential receptor-induced signaling responses – termed bias – potentially by eliciting different levels of recruitment of effector pro...

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Detalles Bibliográficos
Autores principales: Flöser, Anja, Becker, Katharina, Kostenis, Evi, König, Gabriele, Krasel, Cornelius, Kolb, Peter, Bünemann, Moritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635974/
https://www.ncbi.nlm.nih.gov/pubmed/34851820
http://dx.doi.org/10.7554/eLife.58442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635974/
https://www.ncbi.nlm.nih.gov/pubmed/34851820
http://dx.doi.org/10.7554/eLife.58442

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