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GLP-1 Induces the Expression of FNDC5 Derivatives That Execute Lipolytic Actions

Multiple GLP-1-derived therapeutics are clinically used to treat type 2 diabetes and obesity. However, the underlying mechanism of how these drugs regulate the body weight of obese patients remains incompletely understood. Here, we report that the lipolysis effects of GLP-1 on β cells can depend on...

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Detalles Bibliográficos
Autores principales: Li, Hui, Donelan, William, Wang, Fang, Zhang, Peilan, Yang, Lijun, Ding, Yousong, Tang, Dongqi, Li, Shiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636013/
https://www.ncbi.nlm.nih.gov/pubmed/34869379
http://dx.doi.org/10.3389/fcell.2021.777026