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Combined Analysis of Expression Profiles in a Mouse Model and Patients Identified BHMT2 as a New Regulator of Lipid Metabolism in Metabolic-Associated Fatty Liver Disease

Metabolic associated fatty liver disease (MAFLD) is associated with obesity, type 2 diabetes mellitus, and other metabolic syndromes. Farnesoid X receptor (FXR, NR1H4) plays a prominent role in hepatic lipid metabolism. This study combined the expression of liver genes in FXR knockout (KO) mice and...

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Detalles Bibliográficos
Autores principales: Ma, Yongqiang, Tan, Zhi, Li, Qiang, Fan, Wenling, Chen, Guangshun, Bin, Yangyang, Zhou, Yi, Yi, Junfang, Luo, Xiaohua, Tan, Jieqiong, Si, Zhongzhou, Li, Jiequn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636031/
https://www.ncbi.nlm.nih.gov/pubmed/34869329
http://dx.doi.org/10.3389/fcell.2021.741710