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Anti-Drug Antibodies in Pigtailed Macaques Receiving HIV Broadly Neutralising Antibody PGT121

Broadly neutralising antibodies (bNAbs) may play an important role in future strategies for HIV control. The development of anti-drug antibody (ADA) responses can reduce the efficacy of passively transferred bNAbs but the impact of ADA is imperfectly understood. We previously showed that therapeutic...

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Detalles Bibliográficos
Autores principales: Lee, Wen Shi, Reynaldi, Arnold, Amarasena, Thakshila, Davenport, Miles P., Parsons, Matthew S., Kent, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636046/
https://www.ncbi.nlm.nih.gov/pubmed/34867979
http://dx.doi.org/10.3389/fimmu.2021.749891