Autophagy-Induced HDAC6 Activity During Hypoxia Regulates Mitochondrial Energy Metabolism Through the β-Catenin/COUP-TFII Axis in Hepatocellular Carcinoma Cells

Hypoxia is one of the main driving forces that results in poor outcomes and drug resistance in hepatocellular carcinoma (HCC). As the critical cellular oxygen sensor, mitochondria respond to hypoxic stress by sending retrograde signals to the nucleus that initiate adaptive metabolic responses and ma...

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Detalles Bibliográficos
Autores principales: Yan, Xiaoyu, Qu, Xianzhi, Liu, Buhan, Zhao, Yuanxin, Xu, Long, Yu, Sihang, Wang, Jian, Wang, Liying, Su, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636061/
https://www.ncbi.nlm.nih.gov/pubmed/34868939
http://dx.doi.org/10.3389/fonc.2021.742460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636061/
https://www.ncbi.nlm.nih.gov/pubmed/34868939
http://dx.doi.org/10.3389/fonc.2021.742460

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