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Hippocampal Transcriptome-Wide Association Study Reveals Correlations Between Impaired Glutamatergic Synapse Pathway and Age-Related Hearing Loss in BXD-Recombinant Inbred Mice

Age-related hearing loss (ARHL) is associated with cognitive dysfunction; however, the detailed underlying mechanisms remain unclear. The aim of this study is to investigate the potential underlying mechanism with a system genetics approach. A transcriptome-wide association study was performed on ag...

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Detalles Bibliográficos
Autores principales: Deng, Tingzhi, Li, Jingjing, Liu, Jian, Xu, Fuyi, Liu, Xiaoya, Mi, Jia, Bergquist, Jonas, Wang, Helen, Yang, Chunhua, Lu, Lu, Song, Xicheng, Yao, Cuifang, Tian, Geng, Zheng, Qing Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636065/
https://www.ncbi.nlm.nih.gov/pubmed/34867157
http://dx.doi.org/10.3389/fnins.2021.745668