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Muribaculaceae Genomes Assembled from Metagenomes Suggest Genetic Drivers of Differential Response to Acarbose Treatment in Mice

The drug acarbose is used to treat diabetes and, by inhibiting α-amylase in the small intestine, increases the amount of starch entering the lower digestive tract. This results in changes to the composition of the microbiota and their fermentation products. Acarbose also increases longevity in mice,...

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Detalles Bibliográficos
Autores principales: Smith, Byron J., Miller, Richard A., Schmidt, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636109/
https://www.ncbi.nlm.nih.gov/pubmed/34851167
http://dx.doi.org/10.1128/msphere.00851-21